General Reccommendations
Neither of them are interested in romance right now. Maybe. If one of them asked the other, I suspect the answer would be "yes." But both of them live pretty far apart, and long-distance relationships rarely work. Especially fledgeling ones like Keitaro and Konata, both of whom are strangers to romance, galge games not included. Now if Konata goes to the Sou, and lives with Keitaro in the future? Sure, I could see it happening.
Hopefully either the "Promise Girl" deal is either erased, or is greatly toned down, to give Konata and Keitaro a chance. Or hell, when Konata is told that he doesn't even remember who she looks like, just that they will go to Tokyo U with him, she might use her Genre Savvyness (which is sometimes Wrong), think it's a fetish of some sort go to Tokyo U. Or put on a typical student outfit with glasses to try and entice him. After all, we know from Lucky Star that while Konata is a major Otaku and can say ridiculous things as a result., she is also pretty smart when she wants to be, able to get consistently high grades in tests and homework even though she spends barely any time studying.