Probably been talked about before, but there are a number of anime and manga where at least one character is an orphan, usually living completely on their own, even though they are still relatively young with seemingly no adult supervision. We have Makoto Kino, Chitose Hitose (from Happy Lesson), Orihime Inoue, Naruto Uzumaki, Sasuke Uchiha, there are probably others.
Honestly, what's going on?
Honestly, what's going on?