We don't know that much about how Isshin and Masaki met, but what if they didn't, and Ryuken (Ryuko?) was born female. They met in medical school, fell in love, and married, having two sons and two daughters.
The end result is Uryu and Ichigo training as Quincy, and having the prodigious stores of natural spiritual energy Ichigo has canonically.
Things start diverging wildly once they meet Rukia.
The end result is Uryu and Ichigo training as Quincy, and having the prodigious stores of natural spiritual energy Ichigo has canonically.
Things start diverging wildly once they meet Rukia.