A cat-humanoid Chimera ant, the first born of the King's three royal guards. Nefelpitou's (Neferpitou in the Viz Media translation) 'En' is irregularly shaped; rather than a sphere, it takes the form of spiky tendrils of nen, a single one of which can be extended up to two miles. He also has an ability called "Doctor Blythe", which has no use whatsoever outside of healing. Doctor Blythe cannot move from the position which it is initially summoned and it is connected to Pitou's tail, which limits Pitou's radius of movement to 20 meters while it is active. Nefelpitou killed Kaito and had later revived him as a puppet using his abilities--repairing human body parts and puppeteering. Nefelpitou gets distracted easily and loves to play a lot. He is the most naive, or rather simple-minded of the three Royal Guards.
Despite his cheerful and seemingly naive manner, he has been shown to have terrifying power and have a level of extreme sadism. Kaito, Gon, Killua, and other hunters have commented that his power is unlike anything they've ever sensed before. Even the Hunter Association President Netero, who in his younger days was considered the world's strongest nen user, wondered aloud whether Pitou might be stronger than him.[15]
Due to Nefelpitou's very feminine appearance, as well a reference to his stance being 'mother-like' when healing Komugi, there is some confusion as to Pitou's gender. However, in the official Hunter's Guide, Nefelpitou is confirmed as being male.