Well, I just got semi up to date.
The biggest thing is that Anya has shown up. I see her taking Honya and Yuekichi under her wing. Other than that guess, I have no idea how this is going to affect the status quo.
Also, Ayaka is following team Negima to Britain. Naturally, this will end up with her, the twins, Yuuna, Makie, Ako, and Akira learning about magic and joining the ranks.
Speaking of Yuuna, we now know her parents are mages (was in her mother's case.) And one of the flashbacks show her with a training wand as a kid.