Here's my theory on the Twin Drive system, an epiphany I had after watching ep 10. Note that a lot of this is conjecture, based of Wikipedia, and seemingly irrelevant stuff. Possible spoiler warnings, though I won't be so conceited so as to believe I come even remotely close to the real stuff.
I think that the Twin Drive system is 00's Zero system. However, instead of connecting its pilot to the world of infinite possibilities, Twin Drive connects the pilot to literally the "world" itself- people's thoughts. A lot of this theory is based of the except on the Gundam 00 Wikipedia entry that has someone comparing this to a modern adapted version of Gundam Wing, which I personally think makes a lot of sense given the large similarities between the series.
One of the biggest questions so far in the series has been, what are the GN particles? They've been proven to be able to form physical shields/barriers, disrupt transmissions, and of course, power the Gundams and their weapons. Based off episode 10, I am also willing to belive that GN particles can transmit thoughts in the form of quantum brainwaves.
The thought first struck me at the end of episode 10. We see the two people capable of understanding and using quantum brainwaves, Allelujah and Marie, go under some crazy shit. Marie somehow sees the death of Colonel Smirnov thousands of miles away while Hallelujah is revived. Of course, all this happens in areas with a high concentration of GN particles; 00's 0-Raiser test is releasing phenomenal amounts of GN particles and I think Memento Mori is a giant laser of concentrated GN particles (probably wrong on this point). Hallelujah actually even says (according to the gSS subs) "The particles are speeding up toward me...Damn it, can't even let me sleep quietly." This made me think that GN particles are somehow capable of transmitting or amplifying quantum brainwaves.
Here's where it gets a little sketchy. IF GN particles are capable of interacting with quantum brainwaves, what ramifications does this have for the Twin Drive System, whose main purpose is to generate ass-loads of GN particles? It means that Gundam 00 becomes the conduit for the entirety of humanities' thoughts. Remember that quantum brainwaves can read the emotions and feelings of normal people; Marie does this earlier in 00 with Louise.
This, taken in the context of 00, actually makes a surprising amount of sense. A major theme in 00 is to unify the will of the world- how better to do it than by forming a collective conscience? Suddenly, Setsuna's constant referral to Gundam as a separate entity has a deeper meaning- Gundam represents the unified will of the world. Aeolia's final ace was to create a means of unifying the world without using force, by circumventing any obstacles and simply creating a place where all thoughts could come together. Gundam and it's pilot then become the executors of this will. He doesn't only entrust his will with the Gundam Meisters, but the entire world's.
Some supplementary stuff that could be considered making mountains out of molehills:
First, further evidence that GN particles react with quantum brainwaves. In ep 2, even after installing Exia's GN drive, the Twin Drive System doesn't work until Setsuna actually says "Awaken 00" or something along those lines (too lazy to go back and check). You can either believe that by forcing it into Trans-Am Setsuna gave 00 a "jumpstart" or that his thoughts, his emotions caused 00 to awaken. This theory is further supported by the title of the upcoming Ep 11, "Daburu- no Koe" or "Voice of 00."
Second, more stuff on 00 as a conduit. This might seem really extraneous, but in the ED "Prototype" the song refers to a "hikari no sonzai" or literally, a being of light. The line translated as a whole (courtesy of gSS) is "The being of light resting within the glass case is so hard to perceive." As a GN particle generator, 00 is quite literally, an existence of light particles. It certainly looks that way when it awakens in Ep 2. 00 is turned into a "being" through the collection of human thought perceived through GN particles. Yes, I know that ED/OPs aren't necessarily tailored to deep content in the anime itself, but it's worth a shot.